Description: With functionality and style in mind we created our cold therapy gloves and booties for chemotherapy to help in possibly preventing the side effect of neuropathy while undergoing your chemotherapy treatment. We suggest freezing the cold packs overnight up to 3 hours before treatment and begin using them 10 minutes before your infusion begins. If the cold packs start to lose their chill, you can always replace the cold pack with the additional pack halfway through the treatment.